IntroductIon to Molecular BIology and genetIc engIneerIng Oliver Brandenberg

Introduction to Molecular Biology and Genetic Engineering is a foundational text created by Oliver Brandenberg, Zephaniah Dhlamini, Alessandra Sensi, Kakoli Ghosh, and Andrea Sonnino. Designed as a comprehensive guide, this book offers students, researchers, and professionals a clear and systematic overview of the principles, techniques, and applications of molecular biology and genetic engineering.

The text begins with the fundamentals of molecular biology, exploring the structure and function of DNA, RNA, and proteins. It explains core processes such as replication, transcription, and translation, laying the groundwork for understanding how genetic information is stored, expressed, and regulated within living systems. By establishing these molecular basics, the authors prepare readers to grasp more advanced biotechnological concepts.

Building on this foundation, the book transitions into the field of genetic engineering. It introduces essential laboratory techniques such as recombinant DNA technology, cloning, polymerase chain reaction (PCR), and electrophoresis. Each method is explained step by step, often with practical examples that demonstrate how these tools are applied in research, medicine, and agriculture. Special attention is given to the ethical and safety considerations surrounding modern biotechnology, encouraging critical thinking about its societal impact.

One of the strengths of this work lies in its accessibility. The authors balance scientific detail with clear explanations, making the material approachable even for readers with limited prior knowledge. Diagrams, illustrations, and problem-based examples support the text, enhancing comprehension and providing visual clarity.

In addition, the book explores the applications of genetic engineering in fields such as crop improvement, disease resistance, vaccine development, and industrial biotechnology. By connecting theory with practice, it emphasizes the relevance of molecular biology to pressing global challenges in food security, health, and sustainable development.